DOI: 10.62796/pijst.2024v1i8003

  DOI URL: https://doi.org/10.62796/pijst.2024v1i8003

Abstract- A new series of schiff’s bases were synthesised by the condensation of cycloadditition of schiff bases with chloroacetyl chloride and triethylamine in dioxane to afford the corresponding azetidinones, similarly various azitidinones were synthesised. The compounds were characterised by elemental analysis, IR and NMR spectra and were tested for their fungicidal activities. Schiff bases possess diversified biological applications, various 2-azetidinones shows a variety of pharmacological and microbiological activities. Morever compounds containing 2-azetidinones ring system are shown to possess market biological activities1 particularly Fungicidal activity2,3. The present paper reports the synthesis of some new bases 2-azetidinones4. The Schiff bases on reaction with chloroenetyl chloride in dioxane in the presence of triethyl amine yielded 2-azetidinones.